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Renew, Restore, Regenerate: The Exosome Stem Cell Transformation is here

exosomes, stem cells

I’m thrilled to share some incredibly exciting news with you. When it comes to exosomes, I can’t help but feel a deep sense of enthusiasm. Why, you ask? Well, I’ve personally experienced the remarkable benefits of exosomes in my own journey. From regrowing my hair to bidding farewell to those pesky wrinkles, especially those around the eyes, exosomes have been nothing short of a game-changer.

In my view, exosomes are the future of medicine and rejuvenation aesthetics. The ongoing research into exosomes for a multitude of conditions is nothing short of mind-blowing. However, here at OneStopAging, we remain unwavering in our commitment to the pursuit of longevity.

With this blog post, we aim to equip you with all the knowledge you need about exosomes, enabling you to make an informed decision about whether they might play a role in your own anti-aging journey. So, let’s dive into the incredible world of exosomes and what they hold for the future of rejuvenation and longevity.


Imagine exosomes as tiny, magical messengers that facilitate crucial conversations between your cells, ensuring they work harmoniously and efficiently. Now, picture this: when we introduce exosomes derived from the miraculous source of human umbilical cord tissues, it’s like sending a rejuvenating memo to our aging cells. This memo inspires them to not only repair but also replicate, transforming into vibrant, youthful counterparts. These exosomes come bearing gifts—gifts of anti-inflammatory prowess and the potential to breathe new life into tired or damaged tissues. How? By delivering these rejuvenating signals to the cells that need it most. You see, Mesenchymal Stem Cells (MSCs) are innate healers within us, but their numbers dwindle with age. By replenishing our bodies with them, we unleash a whirlwind of accelerated healing. It’s a process that promotes tissue restoration, orchestrates a symphony of inflammation modulation, and fortifies our immune responses. The result? A healthier, more vibrant you.

How do they work?

Picture this: When MSC exosomes are delicately administered to a targeted area, like an injured or weary tissue, they become the catalyst for a remarkable transformation. These exosomes, laden with bioactive molecules, seamlessly infiltrate neighboring cells. Once inside, they orchestrate a symphony of effects, tinkering with gene expression, supercharging protein synthesis, and fine-tuning cellular functions.

The result? A dazzling cascade of benefits.

Tissues on the mend, inflammation receding like a distant memory, and the birth of brand-new blood vessels, all coming together to stage a grand revival and rejuvenation in the wounded region.

Science has set sail on a voyage of discovery, exploring the boundless potential of stem cell-derived exosomes. From rescuing peripheral nerves to aiding in traumatic brain injuries, from championing wound healing to igniting bone fusion, their versatility knows no bounds. It’s not just about rejuvenating tissues; it’s about restoring hope. However, it’s important to remember that, as of today, the FDA is yet to approve exosome products in the United States.

But the future? It promises to be nothing short of extraordinary.

Where do Exosomes come from?

Imagine for a moment the marvel of MSC exosomes – these are like intricate nano-packages brimming with potential, the secret creation of specialized cells called mesenchymal stem cells (MSCs). These exceptional MSC stem cells, the very essence of resilience, are harvested from the remarkable Wharton’s Jelly found within the human umbilical cord.

Wharton’s Jelly, a steadfast guardian of umbilical vessels during fetal development, reveals a secret of its own: a shield of youthfulness, warding off the ravages of aging, environmental toxins, and diseases.
What’s even more astonishing is the origin of these exosomes – nestled in the heart of Baton Rouge, Louisiana, at a women’s clinic. Here, umbilical cords are generously donated by mothers who’ve experienced the gift of healthy full-term pregnancies, making these exosomes not just remarkable but also a symbol of hope.

Exosmoes vs Stem Cells

Exosomes, with their diminutive size, hold immense potential as carriers for delivering therapeutic payloads throughout the body, a challenge often faced by larger stem cells. These minuscule vesicles excel at traversing the blood-brain barrier, enabling precise targeting of specific cells and tissues. In contrast to stem cells, exosomes don’t possess the innate ability to transform into diverse cell types. Instead, they exert their influence by delivering their cargo to target cells, fine-tuning cellular functions, and igniting the machinery of tissue regeneration.

What’s particularly remarkable is that exosomes don’t carry live DNA. Surprisingly, many of the therapeutic benefits attributed to stem cells actually originate from the actions of these exosomes they release. This unique characteristic sets exosomes apart as a superior choice, offering a safe and exceptionally effective approach to tissue repair and rejuvenation.


While a standard PRP injection usually offers up to 12 growth factors to the treatment area, exosome injections, in striking contrast, introduce a substantially larger number, boasting around 700 growth factors. This makes exosome therapy potentially up to 60 times more potent and efficacious compared to PRP treatment.

Exosomes vs PRP

In general, the presence of inflammatory agents can undermine effectiveness, and PRP is categorized as one such agent due to its inflammatory properties. This presents a challenge where treatments might counteract each other, akin to combining outdated and state-of-the-art components. When PRP is administered, it initiates inflammation in nearby tissues, causing exosomes to be redirected to unintended areas, thereby affecting their ability to perform at their best. Essentially, this problem stems from the inflammation triggered by PRP, leading to exosomes being misdirected, ultimately resulting in less-than- optimal results.

Joining Forces with Supreme Rejuvenation: Elevating the Exosome Experience

After extensive research and countless conversations, I’m proud to announce my partnership with Supreme Rejuvenation LLC. Selecting the right company was a meticulous process for me, and I couldn’t be more satisfied with this choice. What sets Supreme Rejuvenation apart is their unwavering commitment to delivering top-quality products and services, all while prioritizing customer satisfaction. Their company culture aligns seamlessly with my values and expectations.

At Supreme Rejuvenation, we’re dedicated to providing only FDA 351(a) drug regulation compliant Regenerative Medicine Products. We take immense pride in being the first company to meet regulatory compliance as a Biologic Drug for Research and Investigational Purposes. This partnership is more than just collaboration; it’s a shared commitment to the future of rejuvenation and longevity. I’m excited to embark on this journey with Supreme Rejuvenation, and I can’t wait to share more about the remarkable world of exosomes with you.

Supreme Standards: Elevating Quality and Safety in Exosome Production


When you submit a Drug Master File, you’re not just fulfilling a requirement; you’re making a resolute statement about your dedication to both regulatory excellence and unwavering quality assurance. This submission opens the doors for the FDA to access vital information, enabling them to conduct a comprehensive evaluation of the product’s safety, efficacy, and overall quality. It’s more than a file; it’s your commitment to transparency and the highest standards.


A third-party virology report for our exosomes stands as an essential pillar in ensuring their safety and quality. Each batch undergoes rigorous testing by an independent third-party company, meticulously guarding against any potential viral contamination. This report isn’t just paperwork; it’s a beacon of transparency and assurance that guides both the development and application of our exosomes.


Our products are meticulously crafted within ISO-5 cleanrooms, housed in CGMP facilities stringently regulated and overseen by the FDA.


Some exosome brands employ a preservation method known as “lyophilization.” Lyophilization is a drying process that removes water from a sample through sublimation. It involves freezing the sample and subjecting it to a vacuum. However, it’s important to highlight that the cell’s delicate bilipid layer is highly sensitive, and lyophilization disrupts this layer.

While lyophilization offers stability at room temperature, the reconstituted product lacks the necessary chemical structure to maintain this stability. Furthermore, the introduction of chemicals during this process means that the resulting product isn’t entirely pure. Beyond potential operational inefficiencies in your clinic’s workflow, there is currently no scientific evidence supporting the idea that lyophilized exosomes have the same payload and effectiveness as non-lyophilized exosomes.

No scientific tests in the lyophilized exosome market have demonstrated the preservation of the initial mRNA and miRNA payload or their efficacy upon reconstitution. For these reasons, our exosome research lab has chosen not to employ this manufacturing technique.


Patient outcomes can vary, but it’s common to see the benefits of exosome therapy lasting for several years after the treatment plan is completed. The specific results depend on the patient’s unique health concerns and medical condition. In some cases, as few as 1-2 therapy sessions may resolve certain health issues, while others may require an ongoing treatment plan for optimal results. The timing of results can also differ, with some patients experiencing improvements almost immediately, while for others, the full effects of treatment may become noticeable within 3-6 months post-treatment.

Exclusively available for research purposes, our exosomes are derived from human umbilical cord stem cells and find applications in various areas, including:

• Acne & Acne Scars • Aging • Bell’s Palsy • Burns/Wounds • Erectile Dysfunction/Male Enhancement (P-Shot) • Endometriosis • Enlarged Pores • Glaucoma • Hair Loss • Hyperpigmentation • Inflammation • Infertility • Melasma • Poor Skin Elasticity • Sagging Skin • Sexual Dysfunction • Skin Regeneration • Sun Damage • Uneven Skin Texture • Vaginal Rejuvenation (O-Shot) • Wrinkles and Fine Lines”

Exosome Stem Cell
Exosome Stem Cell
Exosome Stem Cell

Exclusively available for research purposes, our exosomes are derived from human umbilical cord stem cells and find applications in various areas, including:

• Autoimmune Illnesses • Bone Fractures • Bone Fusion & Regeneration • Cartilage Regeneration (i.e. Meniscus tears) • COVID-19 Long-Haulers • Dementia • Injured Ligaments/Tendons (i.e. ACL tears) • Joint/Systemic Inflammation (i.e. Arthritis) • Multiple Sclerosis • Muscle Strains & Tears • Orthopedics • Osteoarthritis • Overuse Injuries (i.e. Shin Splints) • Peripheral Nerve Damage • Plantar Fasciitis • Rotator Cuff Injuries • Spinal Cord Injuries • Stroke • Tendinitis and Tendinopathy • Tissue Repair • Traumatic Brain Injury • & more…

Contact info: 310-382-6067 Text or Call
Email: info@onestopaging.com

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